Why Calocurb?

Calocurb, the better option for your patients

Grounded in rigorous science, Calocurb employs an innovative approach to naturally regulate appetite and cravings, offering uncompromising support for weight management.

Clinically proven

30% reduction in hunger

New Zealand Bitter Hops Extract Reduces Hunger During a 24h Water Only Fast. Nutrients 2019, 11(11), 2754

40% reduction in cravings

Gastrointestinal Delivery of Bitter Hops Extract Reduces Appetite and Food Cravings in Healthy Adult Women Undergoing Acute Fasting.Obesity Pillars 2024, 100117

18% reduction in calories consumed

An Extract of Hops (Humulus Lupulus L.) Moderates Gut Peptide Hormone Secretion and Reduces Energy Intake in Healthy-Weight Men: A Randomized, Cross Over Clinical Trial.The American Journal of Clinical Nutrition 2022, 115(3), 925-940

Read the Clinical Studies

Safe and natural ingredients

All natural. No synthetic additives

Our three ingredients, including the capsule, are 100% plant-based and certifiably vegetarian, vegan and gluten-free. Amarasate is free from impurities or phytoestrogens and is blended with rosemary and canola oil in a USA GMP accredited plant.

Triggers natural responses within the body

Calocurb stimulates the release of your own satiety hormones (CCK, GLP-1, and PYY) by up to 6 times baseline levels due to the capsule’s unique characteristics.

Works with the body's physiology

Our 125mg capsules allow people to customise their dosage to best fit their body’s needs and gastric emptying rate.

Form the habit, change a life

Long-Term Habit Formation

Seamlessly integrates into patients daily routine increasing the likelihood of continued use.

Patient Flexibility

Personalized dosages can be altered depending on patient and personal responses.

Taken daily, adapt frequently

Designed with minimal side effects, this product facilitates a smoother transition to effective appetite control. Most users notice their body adapting within the first three days, simplifying the management of cravings.

How Calocurb works

After only one hour, Amarasate® stimulates the bitter taste receptors (TAS2R) receptors found on enteroendocrine cells to release gastric hormones (GLP-1 and CCK) at 6 times baseline levels, twice the normal post-prandial release. Overall, the main satiety hormones (GLP-1, CCK and PYY) feature enhanced release with the activation of TAS2R along the small intestine.

These gastric hormones signal a part of the brain to decrease appetite and food cravings plus slow down the gastric emptying rate.

Due to the delayed release of Calocurb into the small intestine, over 99% of Amarasate is metabolized in the large colon, bypassing the entrance into the bloodstream or hepatic system.

Our Supply Chain

Calocurb Pure Manufacture

Our dedication to purity takes root in the gentle harvesting of our GRAS approved New Zealand hop flowers (Humulus Lupulus). The patented formulation is milled, pressed, and extracted from 100% organic NZ whole hop flowers without harsh chemicals through the CO2 supercritical extraction process. Our Amarasate® is free from impurities or phytoestrogens. Blended with rosemary and canola oil in a USA GMP accredited plant, our 3-ingredient natural formulation is the essence of natural elegance and simplicity.

The Perfect Capsule

Not all capsules are created equal. Our acid-resistant vegetarian capsules ensure that Calocurb releases its power at just the right spot in the body. Licaps® two-piece capsules are an advanced dosage form offered in HPMC (hypromellose) format, designed by the world-leading Capsugel team in Greenwood, SC, allowing Calocurb to start working in just one hour. Lonza, the largest capsule manufacturer in the world has Good Manufacturing Practice, National Sanitation Foundation and FDA approval in the USA manufacturing plant.

Exported Globally

Calocurb is manufactured and distributed in the USA. Calocurb continues to grow in both areas of B2B and D2C and exported globally. We are dedicated to promoting Calocurb on Fullscript.

Join Practitioners in choosing Calocurb

Become part of a growing community of practitioners who advocate for Calocurb as their preferred choice for natural GLP-1 activation.

Order samples today